Subject description - BEAM02BIO

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BEAM02BIO Biosensors Extent of teaching:2P+2L
Guarantors:  Roles:PV Language of
teaching:
EN
Teachers:  Completion:Z,ZK
Responsible Department:13102 Credits:6 Semester:Z

Anotation:

This course introduces general principle of biosensors and their physical, electronic and biological mechanisms. It provides information on past, present and future technologies. Different mechanisms and concepts of sensors for specific applications such as glucose, urea, proteins, cells, bacteria, etc. will be explained. In addition, the course introduces the use of modern nanostructures and nanomaterials in biosensors to provide convenient, reliable and sensitive devices for point of care diagnosis as well as for food and environmental monitoring. Finally, this course will discuss current challenges and future perspectives in various biosensor applications.

Content:

This course introduces general principle of biosensors and their physical, electronic and biological mechanisms. It provides information on past, present and future technologies. Different mechanisms and concepts of sensors for specific applications such as glucose, urea, proteins, cells, bacteria, etc. will be explained. In addition, the course introduces the use of modern nanostructures and nanomaterials in biosensors to provide convenient, reliable and sensitive devices for point of care diagnosis as well as for food and environmental monitoring. Finally, this course will discuss current challenges and future perspectives in various biosensor applications.

Course outlines:

1. Overview of biosensors - Introduction and concept of biosensor
2. Biosensor development - ideal biosensor characteristics
3. Bioreceptor - catalytic (equilibrium) and affinity (equilibrium)
4. Surface Function - Physical and Chemical Immobilization
5. Electrochemical and Electrochemiluminescence - Overview and Applications
6. Optical - fluorescence and colorimetric study
7. Field controlled transistors - Sensors and applications
8. Nanobiosectors - top down (nanostructures)
9. Nanobiosectors - bottom up (nanomaterials)
10. BioMEMS / NEMS - Microfluidic, SAW
11. Application of biosensors - market for health care
12. Reliability of biosensors - in food and environment
13. New trends in biosensors - wearable biosensors, laboratory on chip
14. Current global biosensors challenges and future developments, final summary

Exercises outline:

Literature:

[1] Introduction to Biosensors, Essays in Biochemistry 2016, doi:10.1042/EBC20150001
[2] Biosensors, InTech 2010, ISBN 978-953-7619-99-2, doi:10.5772/45616
[3] Biosensors: fundamentals and applications, Oxford University Press 1989, ISBN 0198547455, open access

Requirements:

Students pass the exam by written test and oral examination. Students prepare reports from laboratory exercises.

Subject is included into these academic programs:

Program Branch Role Recommended semester
MEBIO_2018 Common courses PV


Page updated 6.12.2019 17:52:32, semester: Z,L/2020-1, L/2018-9, Z,L/2019-20, Send comments about the content to the Administrators of the Academic Programs Proposal and Realization: I. Halaška (K336), J. Novák (K336)